Jamie McDonnell will fight Mexican Julio Ceja for the vacant IBF bantamweight title on May 11 at Keepmoat Stadium, the home of the club he supports Doncaster Rovers.
Fight promoter Dennis Hobson said that he and McDonnell were "delighted" to have secured the venue as Ceja was keen for it to be held in Mexico.
"I am delighted to be bringing the world title fight to the Keepmoat Stadium," Sky Sports News quotes Hobson as saying. "Both Jamie and I have long been determined for his world title fight to take place at his home stadium.
"Ceja's camp really wanted the fight to be staged in Mexico and we had to work really hard to bring this fight to South Yorkshire. The facilities at the Keepmoat Stadium are fantastic and Jamie is exceptionally proud to be showcasing Doncaster and the stadium to the world.
"We would love Jamie to be crowned the first boxing world champion from Doncaster in his home town on May 11."
The 26-year-old has 16 wins from his 18 professional bouts.