Arsenal head into this week's Champions League meeting with Anderlecht three points behind Group D leaders Borussia Dortmund, needing a win to keep up the pressure on the Germans.
Arsene Wenger's side are looking to make it two wins in as many weeks over the Belgians, but they did it the hard way in the reverse fixture, needing two late goals in a 2-1 triumph.
The Gunners head into the match off the back of a 3-0 win over Burnley and will be hoping for more of the same from striker Alexis Sanchez, who netted twice against the Premier League's basement boys.
Goalkeeper Wojciech Szczesny missed the game in Belgium through suspension, but will reclaim his place between the sticks after keeping a clean sheet against Burnley.
Jack Wilshere could return to the Gunners' midfield after sitting out of the victory against Sean Dyche's side, featuring in the centre of the park alongside Aaron Ramsey.
Alex Oxlade-Chamberlain may be sacrificed to make way for Wilshere, while a lengthy injury list could force Wenger to use Nacho Monreal as a makeshift centre-back once again.
Anderlecht are in somewhat shaky form of late, but lead the way in their domestic league by a single point after 13 matches.
However, their dismal record of just six wins in 29 attempts against English opposition makes Arsenal the clear favourites.
Recent form
Arsenal: WDLWDW
Anderlecht: DDLLWD
Possible starting lineups
Arsenal: Szczesny; Chambers, Mertesacker, Monreal, Gibbs; Arteta, Wilshere, Ramsey; Cazorla, Sanchez, Welbeck
Anderlecht: Proto; Vanden Borre, Mbemba, Heylen, Deschacht; Defour, Tielemans; Najar, Praet, Suarez; Mitrovic
Sports Mole says: 2-0
Mark Langshaw
