Johan Djourou has become the latest Arsenal player to be sidelined with an injury.
The Swiss international suffered a groin problem during Sunday's 1-0 defeat to Manchester City and will now miss tomorrow's trip to Aston Villa.
Djourou's absence has left Wenger without a recognised a full-back for the match at Villa Park.
Kieran Gibbs, Andre Santos, Carl Jenkinson and Bacary Sagna have all been out for some time and it is not anticipated that they will return until after Christmas.
Ignasi Miquel or Sebastien Squillaci are expected to deputise.