Jeremy Toulalan has been selected in the AS Monaco defence as they welcome Lyon to the Stade Louis II.
Ricardo Carvalho and Andrea Raggi are both suspended for the hosts, while Fabio Coentrao is missing due to an injury picked up on international duty with Portugal.
The defensive crisis has forced Leonardo Jardim to start with Toulalan at the back, which gives Mario Pasalic the opportunity to join Joao Moutinho in central midfield.
Lyon welcome back Mapou Yanga-Mbiwa as a replacement for the injured Milan Bisevac in defence, while the visitors are also without Aldo Kalulu, who could miss two months with an ankle injury.
There are starts for Alexandre Lacazette, Mathieu Valbuena and Sergi Darder as Lyon search for a win that would take them up to second in the table.
AS Monaco: Subasic, Fabinho, Wallace, Toulalan, Elderson, Pasalic, Moutinho, Silva, Lemar, Cavaleiro, Traore
Subs: Nardi, Diarra, Lopes, Boschilia, Mexique, Carrillo, El Shaarawy
Lyon: Lopes, Jallet, Yanga-Mbiwa, Umtiti, Rafael, Gonalons, Darder, Tolisso, Valbuena, Beauvue, Lacazette
Subs: Gorgelin, Rose, Ferri, Malbranque, Mvuemba, Ghezzal, Cornet