Empoli vs. Fiorentina (Sunday, 5.30pm)
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Contesting a Tuscan derby in their first away match of the season, Fiorentina take the short trip to Empoli on Sunday evening.
While the Viola have started their 2022-23 campaign with wins in Serie A and in Europe, their hosts have suffered successive defeats to continue a miserable calendar year.
We say: Empoli 1-2 Fiorentina
While Fiorentina can be fragile defensively - and fatigue could be a factor following Thursday's efforts - their attacking prowess under Vincenzo Italiano should earn them maximum points from this local affair; Empoli's sorry streak is set to roll on.
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Napoli vs. Monza (Sunday, 5.30pm)
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After a thumping victory on the opening day, Napoli tackle their first home fixture of the Serie A season as they welcome Monza to Stadio Maradona on Sunday.
Having found the net five times in Verona - each time through a different scorer - the Partenopei are primed to meet a promoted side who have been ambitious in the transfer market.
We say: Napoli 2-0 Monza
Already with an abundance of goalscoring options from almost anywhere around the XI, Napoli have strengthened again this week, and should have too much firepower for Monza to handle.
The visitors have been handed a tough start to Serie A life, and are not yet in the kind of shape that could see them upset the established order.
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Bologna vs. Hellas Verona (Sunday, 7.45pm)
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Both beaten on the opening day, Bologna and Hellas Verona aim to get off the mark in Serie A this season, as they meet at Stadio Renato Dall'Ara on Sunday.
While the hosts threw away a goal and a man advantage to lose against Lazio, their visitors were thumped 5-2 by rampant Napoli on home soil.
We say: Bologna 1-1 Hellas Verona
As Bologna generally struggle to score more than once in 90 minutes, they may not possess enough guile to take full advantage of Verona's vulnerabilities at the back. Meanwhile, the visitors are still adapting to life after Giovanni Simeone, so are reduced in firepower themselves.
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Atalanta vs. AC Milan (Sunday, 7.45pm)
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After both enjoyed successful starts to the new Serie A season, Atalanta BC and Lombardy rivals AC Milan clash at the Gewiss Stadium on Sunday evening.
While La Dea took maximum points against Sampdoria on the opening day, the champions extended a long winning run by beating Udinese 4-2 at San Siro.
We say: Atalanta BC 1-2 AC Milan
Always an intriguing match-up, these two sides have clearly defined modes of play and a strongly-held identity. Though pragmatic, Milan's is generally more effective, and they can prolong their winning run by outscoring opponents who can barely buy a win on home turf.