Celtic won their first away match in the Champions League last time out at Spartak Moscow and they could make it two in a row on Tuesday.
However, they travel to the formidable Camp Nou to take on former champions Barcelona, who are unbeaten in 17 home European ties, in by far their toughest Group G encounter.
The trio of Kris Commons, James Forrest and Scott Brown missed out on the Bhoys' 5-0 romp of St. Mirren on Saturday but could be fit to face Barca.
Barcelona head into the match on the back of a remarkable 5-4, ten-man win at Deportivo on Saturday.
Boss Tito Vilanova is likely to ring the changes that could see Xavi Hernandez, Alexis Sanchez, and Pedro all come into the starting lineup.
Recent form
Barca: WDWWWW
Celtic: WWWWWW
Possible starting lineups:
Barca: Valdes; Montoya, Song, Mascherano, Alba; Xavi, Busquets, Iniesta; Sanchez, Messi, Pedro
Celtic: Forster; Matthews, Wilson, Ambrose, Mulgrew, Kayal, Brown, Ledley, Commons; Samaras, Hooper
Sports Mole says: 4-0
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