Belgium vs. Poland (Wednesday, 7.45pm)
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Belgium will hope to avoid being on the wrong end of another humiliating UEFA Nations League defeat when they welcome Poland to Brussels for Wednesday's League A Group 4 showdown.
The Red Devils went down 4-1 to the Netherlands in their inaugural contest, while the visitors just about managed to scrape a 2-1 success versus a much-changed Wales side.
We say: Belgium 2-1 Poland
The footballing gods should not deliver a drab affair between two sides whose defining qualities lie in the final third, although losing top scorer Lukaku is a killer blow for Belgium.
Poland would have expected a greater margin of victory against a makeshift Wales XI, though, and with Martinez issuing a rallying cry to his Belgium side to respond, we have faith in the world's second-ranked nation to get back on track.
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Wales vs. Netherlands (Wednesday, 7.45pm)
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Returning to a party atmosphere in Cardiff, Wales quickly resume their UEFA Nations League campaign with the visit of the Netherlands in League A Group 4 on Wednesday night.
Rob Page guided the Dragons to their first World Cup in 64 years with victory over Ukraine, while Oranje most recently thumped Belgium by four goals to one.
We say: Wales 1-3 Netherlands
The result of Wednesday's game should pale into insignificance for a much-changed Wales side after the weekend's exploits, but Page's second-string XI still performed admirably against Poland.
Changes can also be expected on the visitors' end as they seek to end the Dragons' lengthy unbeaten run at home, but we can only picture Van Gaal's merciless side giving Wales a harsh reality check in Cardiff.
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> How the Netherlands could line up against Wales
Scotland vs. Armenia (Wednesday, 7.45pm)
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Scotland get their UEFA Nations League campaign underway against Armenia looking to bounce back from the disappointment of missing out on the World Cup.
While the Tartan Army endured one of their biggest frustrations in recent years last week, Armenia posted one of their most notable wins in years by defeating Republic of Ireland.
We say: Scotland 1-0 Armenia
Given their recent experiences, this has the potential to be a much closer contest than many people are anticipating. However, while Scotland may take some time to rouse themselves after the Ukraine disappointment, we still expect the Tartan Army to edge this contest, perhaps by the one goal.
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Rep. Ireland vs. Ukraine (Wednesday, 7.45pm)
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Republic of Ireland head into their UEFA Nations League fixture with Ukraine looking to bounce back from the deflating defeat to Armenia over the weekend.
Ukraine will prepare for this League B Group 1 contest having endured significantly more disappointment having lost out to Wales in their World Cup playoff final on Sunday.
We say: Republic of Ireland 0-2 Ukraine
Before the Armenia defeat, we would have fancied Republic of Ireland to collect at least a score draw against opponents who have taken on a high workload over the past week. However, even if Ukraine make changes, we still expect the visitors to claim all three points in Dublin, and in convincing fashion, too.