Coach Jurgen Klopp has recalled Nuri Sahin to his starting lineup for the clash against second-placed Bayer Leverkusen, but Lukasz Piszczek has had to settle for a place on the bench.
Marco Reus has not recovered in time to start, which means that Pierre-Emerick Aubameyang and Jakub Blaszczykowski have been deployed on the flanks.
The visiting Bayer stick with Emre Can out of position at left-back, with Jens Hegeler and Son Heung-Min providing the width in the absence of Sidney Sam.
Dortmund: Weidenfeller; Grosskreutz, Friedrich, Sokratis, Durm; Bender, Sahin; Mkhitaryan, Blaszczykowski, Aubameyang; Lewandowski
Bayer: Leno; Donati, Toprak, Spahic, Can; Bender, Castro, Rolfes; Hegeler, Son, Kiessling
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