© Reuters

Chile come into Saturday's Copa America clash against Brazil without key forward Alexis Sanchez, who has been ruled out indefinitely with an injury picked up immediately before the tournament.

In his absence, their line has been led by Eduardo Vargas, who has netted two goals in four games, helping his side to two points as they drew 1-1 with both group favourites Uruguay and Argentina.

He will be supported by Ben Brereton, who was the hero in their 1-0 win over Bolivia in the group stage, netting his first goal for Chile after committing to the nation prior to the Copa America.

The defence may have also taken a hit though, as key centre-back Guillermo Maripan, who was crucial in the first three group games, missed the final match against Paraguay through injury, and he could miss out again on Saturday.

They still boast a solid and experienced spine though, with midfielders Arturo Vidal and Charles Aranguiz having made a combined 209 apps, while centre-back Gary Medel has appeared for his nation 133 times.

He will attempt to keep it tight and shield former Barcelona goalkeeper Claudio Bravo, who will earn his 133rd cap on Saturday.

Chile possible starting lineup: Bravo; Isla, Medel, Sierralta, Mena; Vidal, Aranguiz, Alarcon; Brereton, Vargas, Pinares

> Click here to see how Brazil could line up for this clash