Manchester City and Chelsea have announced their first XIs for Saturday's Premier League fixture at the Etihad Stadium.
With City having signed three new players over the past week and Chelsea missing three key man for Monday's game versus Wolverhampton Wanderers, there was always the potential for mass changes to each side.
That has how it has transpired with Pep Guardiola handing immediate debuts to the likes of defender Abdukodir Khusanov and versatile attacker Omar Marmoush.
Guardiola has made a total of three changes with Ilkay Gundogan also being brought into the starting lineup. Ruben Dias, Kevin De Bruyne and Savinho are the trio to the drop out of the side.
Fellow new arrival Vitor Reis is named among the replacements to bolster City's options in the second half.
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How many changes have Chelsea made?
Meanwhile, Enzo Maresca has decided to recall Levi Colwill and Enzo Fernandez to his starting lineup for the showdown in the North-West.
Jadon Sancho also starts against his former club on the left flank, with Tosin Adarabioyo, Kiernan Dewsbury-Hall and Pedro Neto the players to miss out.
Reece James starts consecutive Premier League fixtures for the first time since the start of November.
Nicolas Jackson retains his place down the centre of the attack, leaving Christopher Nkunku to remain on the bench.
Manchester City: Ederson; Nunes, Khusanov, Akanji, Gvardiol; Kovacic, Gundogan; Bernardo, Marmoush, Foden; Haaland
Subs: Ortega, Stones, Grealish, De Bruyne, Reis, Savinho, O'Reilly, Lewis, McAtee
Chelsea XI: Sanchez; James, Chalobah, Colwill, Cucurella; Caicedo, Fernandez; Madueke, Palmer, Sancho; Jackson
Subs: Jorgensen, Gusto, Acheampong, Disasi, Tosin, Dewsbury-Hall, Neto, Nkunku, Guiu