Leicester vs. Man City (Saturday, 12.30pm)
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A true test of Leicester City's purple patch awaits them at the King Power Stadium this Saturday lunchtime, as Premier League champions Manchester City pay a visit.
Brendan Rodgers's side convincingly beat Wolverhampton Wanderers 4-0 last weekend, while City were held to a goalless draw in the Champions League by Borussia Dortmund.
We say: Leicester City 1-2 Manchester City
Leicester's upturn in form, Man City's spate of goalless games away from home and concerns over Haaland's fitness makes this a far trickier game for the champions than some may have anticipated, especially with a rejuvenated Vardy seeking to continue his prolific streak against the big boys.
The Foxes' resilient defensive streak is unlikely to count for much either way, and while we have faith in Guardiola's side to get the job done, it would not be surprising to see just the one-goal margin separate the teams.
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> How Man City could line up against Leicester
> Man City injury, suspension list vs. Leicester City
Bournemouth vs. Spurs (Saturday, 3.00pm)
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Two sides who were on the wrong end of controversial VAR calls last time out do battle in Saturday's Premier League clash, as Bournemouth tackle Tottenham Hotspur at the Vitality Stadium.
Gary O'Neil's side were left to rue the handball rule book in a 2-0 loss to West Ham United on Monday, while Spurs dramatically drew 1-1 with Sporting Lisbon in the Champions League.
We say: Bournemouth 0-1 Tottenham Hotspur
Even if the youthful livewire Gil does come in for his first-ever Premier League start, Tottenham's attacking deficiencies will not be solved overnight, especially against a Bournemouth side who tend not to concede many goals at home.
Putting the ball in the back of the net at home has not been one of the Cherries' specialities either, and Saturday's game does not have the look of an exciting encounter, but Conte's side can hold firm and nick the one goal they need against a Neto-less backline to return to winning ways.
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> How Tottenham could line up against Bournemouth
> Tottenham injury, suspension list vs. Bournemouth
Brentford vs. Wolves (Saturday, 3.00pm)
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Brentford host Wolverhampton Wanderers at the Gtech Community Stadium on Saturday, with both teams looking to get back to winning ways in the Premier League.
The Bees lost 4-0 at managerless Aston Villa last weekend, while Wolves lost by the same scoreline at home to Leicester City.
We say: Brentford 1-0 Wolverhampton Wanderers
Brentford will be wanting to respond after the disappointing loss against Aston Villa last week, and we expect them to do so in a narrow victory against Wolves. Given the away side's poor recent form and away record, they are likely to come up short against the Bees, who have been decent at home.
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Brighton vs. Chelsea (Saturday, 3.00pm)
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Graham Potter will return to his old club when Chelsea travel to face Brighton & Hove Albion at the Amex in the Premier League this Saturday.
Roberto De Zerbi is still looking for his first win as Brighton boss since replacing Potter in the role last month.
We say: Brighton & Hove Albion 0-0 Chelsea
Four of the last five encounters between the sides have ended in draws and both have suffered from profligacy in front of goal recently.
Excluding Brighton's 5-2 win over Leicester here, the other four games at the Amex so far this season have yielded just two goals.
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> How Chelsea could line up against Brighton
> Chelsea injury, suspension list vs. Brighton & Hove Albion
Crystal Palace vs. Southampton (Saturday, 3.00pm)
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Separated by just a point in the Premier League table, Crystal Palace and Southampton meet on Saturday afternoon at Selhurst Park.
After posting two wins and a draw from their previous three games, Palace were thumped 3-0 by Everton last time out, while Saints bravely held league leaders Arsenal to notch up a third game without defeat.
We say: Crystal Palace 2-1 Southampton
Given Palace's prowess at Selhurst Park and Southampton's struggles on the road, a home win seems the likeliest outcome on Saturday. A certain amount of frustration carried over from their loss last week should see the hosts start on the front foot, with unstinting support from the stands helping them over the line.
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Newcastle vs. Aston Villa (Saturday, 3.00pm)
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Newcastle United host Aston Villa in the Premier League on Saturday, with momentum building at St. James' Park that the Magpies can break into the top four for the first time in 20 years.
Villa caretaker Aaron Danks will take charge for the last time here before new manager Unai Emery takes the reins next week.
We say: Newcastle United 2-0 Aston Villa
Villa got a huge lift from their result last week, but St. James' Park has become one of the toughest place to visit in the country, so this will be difficult for Danks and his side.
Newcastle have kept three clean sheets in their six home games this season, and they looked very comfortable in defence when they faced Everton in their last fixture here, so a similar result looks likely.
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Fulham vs. Everton (Saturday, 5.30pm)
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Saturday evening's Premier League action comes from Craven Cottage, when an impressive Fulham side host Everton.
Fulham boss Marco Silva will face his former employers for the first time since he was sacked by the Toffees in December 2019.
We say: Fulham 2-1 Everton
Despite a return to form last weekend, Everton's away record remains one of the worst in the country, as they have won only three games on the road since fans were permitted back into stadiums.
Fulham have only lost once at Craven Cottage this season, and while they may struggle to break through Everton's strong defence at will, they have seemingly found a way to score past most teams this season.
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Liverpool vs. Leeds (Saturday, 7.45pm)
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Buoyed by confirming their place in the Champions League knockout stages, Liverpool seek a return to winning ways in the Premier League when Leeds United visit Anfield on Saturday evening.
The Reds ran out 3-0 victors over Ajax to confirm a top-two finish in Group A on Wednesday, while Jesse Marsch's men lost 3-2 to Fulham last time out.
We say: Liverpool 3-0 Leeds United
Asserting their dominance in the Premier League has not been as easy as it has been in Europe recently for Liverpool, but they are unlikely to come under much duress against Marsch's leaky and injury-hit crop.
Klopp could very well choose to go with a stronger lineup here before resting players against Napoli with Champions League qualification already sealed, and travelling Whites fans should prepare for another painful afternoon on Merseyside.
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