Chelsea head coach Enzo Maresca is expected to revert to his regular 'A' team for Tuesday's Premier League clash with Bournemouth at Stamford Bridge.
The Blues' second-string side thumped Morecambe 5-0 in the third round of the FA Cup on Saturday, but almost every starter from that comfortable success should now cede their places.
The alterations begin in goal, where Robert Sanchez will demote Filip Jorgensen down to the bench, while Tosin Adarabioyo's brace is unlikely to earn him a Premier League start.
Instead, Maresca has quickly promoted Josh Acheampong to his first-team ranks after his contract stand-off was resolved, and the teenager is now set to link arms with Marc Cucurella, Malo Gusto and Levi Colwill at the back.
Sweeping changes further up the field will also see Moises Caicedo and Enzo Fernandez resume their midfield partnership, and the only man who might keep his spot from the weekend's thrashing is Pedro Neto.
Noni Madueke would normally be an alternative option out wide, but the England international missed the weekend's FA Cup success owing to illness and is fighting an uphill battle to make the cut this weekend.
As a result, Neto could welcome Nicolas Jackson, Jadon Sancho and Cole Palmer back to the final third for the hosts, who remain without Wesley Fofana (hamstring), Benoit Badiashile (thigh), Mykhaylo Mudryk (suspended), Omari Kellyman (hamstring) and Kiernan Dewsbury-Hall (unspecified).
Chelsea possible starting lineup:
Sanchez; Gusto, Acheampong, Colwill, Cucurella; Fernandez, Caicedo; Sancho, Palmer, Neto; Jackson
> Click here to see how Bournemouth could line up for this clash
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