Chesterfield are missing striker Sylvan Ebanks-Blake ahead of their League One clash against Wigan Athletic at the Proact Stadium.
The former Wolverhampton Wanderers forward is expected to be absent from first-team duty for a week to 10 days with a hamstring strain.
Meanwhile, Gboly Ariyibi has returned from action with the USA Under-23s to line up in the Spireites' starting XI.
The Latics have handed on-loan Newcastle United striker Haris Vuckic his first start for the Lancashire side up front, while Sean Murray and Leon Barnett are also drafted in.
Former Bolton Wanderers defender Andy Kellett, famous for having spent time on loan at Manchester United, makes the bench for his new side, with youngster Tim Chow featuring in a matchday squad for the first time this season.
Chesterfield: Lee, O'Neill, Jones, Hird, Morsy, Evatt, Gardner, O'Shea, Novak, Banks, Ariyibi
Subs: Humphreys, Raglan, Gnanduillet, Harrison, Donohue, Dieseruvwe, Cains
Wigan: O'Donnell, James, Perkins, Daniels, Power, Craig Davies, Jacobs, Murray, Barnett, Pearce, Vuckic
Subs: Jaaskelainen, Kellett, McCann, Odelusi, Flores Chow, Hiwula