Crotone vs. Lazio (Saturday, 2.00pm)
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Still mired in controversy, Lazio travel to bottom side Crotone on Saturday keen to make up lost ground on their main Serie A rivals.
Simone Inzaghi's men are currently ninth in the table as the club hierarchy have faced criticism over their unique approach to COVID-19 testing and, bizarrely, their mid-pandemic 'purchase' of a Boeing 737 aeroplane.
We say: Crotone 1-2 Lazio
Expect Lazio to emerge from a tumultuous period with all guns blazing from the start, while Crotone will have to wait even longer for their first win of the season.
The club based in the ancient Greek settlement of Kroton are simply a tragedy-in-waiting, as their Roman counterparts - with chief weapon Ciro Immobile returning - have more than enough firepower to overwhelm their flimsy defences.
Our tipster partners are predicting over 2.5 goals.
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Spezia vs. Atalanta (Saturday, 5.00pm)
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Atalanta BC welcome back a host of international stars from far and wide, as they journey south to Spezia's temporary home in Cesena for Saturday's Serie A encounter.
Spezia's unexpectedly solid start to life in Serie A continued before the international break, as they cruised to a home victory against fellow top flight new boys Benevento, while Atalanta's rollercoaster form - at home and abroad - has left them sixth in the early standings.
We say: Spezia 2-3 Atalanta BC
Spezia have stood aside for no-one in Serie A so far, defying expectations with a healthy points - and goals - tally. The Bianconeri should take inspiration from their comprehensive win in Benevento last time out.
Their opponents, however, have an increasingly deep squad and Gian Piero Gasperini can make full use of rotation - and the five substitutes rule - to get them over the line in what is set to be a typically open game.
Our tipster partners are predicting over 2.5 goals.
> Click here to read our full preview for this match
Juventus vs. Cagliari (Saturday, 7.45pm)
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Champions Juventus return to Serie A action this weekend when they face Cagliari at the Allianz Stadium on Saturday evening, with a defensive crisis arising just as they face increasingly prolific opponents.
The visitors have netted at least two goals in each of their last five fixtures and have significantly stirred into life after an indifferent start to the season under attack-focused coach Eusebio Di Francesco.
We say: Juventus 2-1 Cagliari
Andrea Pirlo's immediate task is plain - turn Serie A draws into wins as a matter of urgency. His charges can do just that here, given the continuing potency of Cristiano Ronaldo and Alvaro Morata's recent renaissance.
Nonetheless, Cagliari are undoubtedly on the rise and will certainly cause trouble for the Bianconeri's injury-plagued back line when the opportunity arises.
Our tipster partners are predicting a home win.