The Premier League's top two go head to head in the standout fixture of a midweek gameweek 13 as champions Liverpool welcome leaders Tottenham Hotspur to Anfield.
Every member of the 'big six' dropped points at the weekend to open up the table even further, leaving Leicester City and Southampton with the opportunity to go temporarily top in their matches against Everton and Arsenal respectively.
There is also a London derby between West Ham United and Crystal Palace, while Sheffield United will cap off the gameweek hoping for their first win of the season against Manchester United.
Click play below to watch or listen to Sports Mole Editor Barney Corkhill and Football Editor Matt Law discuss their predictions for all 10 matches this week.
Watch the full discussion here:
Or you can listen to the full podcast here:
TUESDAY
6pm - Wolverhampton Wanderers vs. Chelsea (0:22)
8pm - Manchester City vs. West Bromwich Albion (3:10)
WEDNESDAY
6pm - Arsenal vs. Southampton (6:29)
6pm - Leeds United vs. Newcastle United (10:35)
6pm - Leicester City vs. Everton (13:18)
8pm - Fulham vs. Brighton & Hove Albion (16:32)
8pm - West Ham United vs. Crystal Palace (19:25)
8pm - Liverpool vs. Tottenham Hotspur (22:16)
THURSDAY
6pm - Aston Villa vs. Burnley (27:59)
8pm - Sheffield United vs. Manchester United (31:15)