Everton manager David Moyes has said that his midweek Carling Cup team selection has backfired ahead of Saturday's match against Manchester United.
The Toffees fielded a strong side in their 2-1 extra-time defeat against Chelsea on Wednesday, but could now be without Phil Neville and Tim Cahill through injury for tomorrow's clash at Goodison Park.
Royston Drenthe was also sent off against Andre Villas-Boas's side and he is suspended for the match with the Red Devils.
"We took a chance by playing a strong side against Chelsea, to try to get through in the Cup," said Moyes. "I thought that game was the important one at the time and we wanted to do it, but you're always running the risk of losing players through injury.
"You put people out and they get booked or sent off. That is maybe why when it comes to Premier League managers, they see the league as being the most important thing and sometimes the games in the League Cup come second to it.
"We didn't and went out with a strong team, but it has sort of backfired on me because I've had somebody sent off and a few injuries from it."
Everton go into the match in 13th place in the Premier League table, while United are currently second.