Manchester United will be looking to extend their unbeaten run to 14 matches in the Premier League by overcoming bottom side Sheffield United on Wednesday night.
The Red Devils enter the midweek round of games top of the division and are also through to the fifth round of the FA Cup.
Ole Gunnar Solskjaer rotated his side for Sunday's 3-2 cup win over Liverpool and may be tempted to do likewise for the visit of Sheff United.
Here, Sports Mole looks at how United could line up at Old Trafford in midweek.
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Out: Marcos Rojo (calf), Facundo Pellistri (coronavirus), Brandon Williams (knock), Phil Jones (knee)
Doubtful: Marcus Rashford (knee)
> Click here for Man United's latest injury and suspension news ahead of this match
United remain without a number of fringe players, but they may also now potentially be without Marcus Rashford after he limped off late on against Liverpool.
The forward is unlikely to be risked for this game against bottom-side Sheffield United, especially with Anthony Martial and Mason Greenwood available in the wide positions.
Martial, incidentally, has been directly involved in five of the Red Devils' last six Premier League goals against the Blades (four goals and one assist).
Bruno Fernandes came off the bench to see United past Liverpool in the cup at the weekend and is expected to come back into the XI here.
However, Paul Pogba and Scott McTominay may possibly be given a breather, while Luke Shaw is another who could do with a rest, even if he has been in superb form of late.
Up top, Edinson Cavani will have a chance to build on his return of six goal involvements in 12 Premier League appearances.
Video prediction
Watch the Sports Mole Football Shorts prediction for this game below:
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