Anthony Martial will lead the Manchester United line in Saturday's Premier League clash with Bournemouth at Old Trafford.
The Frenchman, who has scored just one Premier League goal this season, is given the nod over Rasmus Hojlund in the final third of the field.
There is also a spot in the team for Sergio Reguilon, who comes in for the injured Victor Lindelof, meaning that Luke Shaw will feature in the middle of the defence.
Antony and Alejandro Garnacho, as expected, keep their spots in the wide positions, while Sofyan Amrabat again features in central midfield.
Marcus Rashford, who is the all-time leading goalscorer in games between Man United and Bournemouth with five goals, had been a huge doubt for the match due to illness, but he is on the bench.
Raphael Varane is also back on the bench after missing the win over Chelsea due to a back issue.
As for Bournemouth, Marcus Tavernier is preferred to Luis Sinisterra, with the latter dropping down to the bench for the league contest at Old Trafford.
Dominic Solanke will again lead the line for Andoni Iraola's side, while Justin Kluivert also retains his spot in the final third of the field.
Manchester United: Onana; Dalot, Maguire, Shaw, Reguilon; Amrabat, McTominay; Antony, Fernandes, Garnacho; Martial
Subs: Bayindir, Evans, Varane, Wan-Bissaka, Mainoo, Pellistri, Van de Beek, Hojlund, Rashford
Bournemouth: Neto; A Smith, Zabarnyi, Senesi, Kerkez; Cook, Christie; Semenyo, Kluivert, Tavernier; Solanke
Subs: Travers, Mepham, Kilkenny, Rothwell, Brooks, Dango, Sinisterra, Moore, Philip