Darren Fletcher will start a Premier League game for the first time in over a year when Manchester United host Queens Park Rangers later this afternoon.
The Scot starts alongside Paul Scholes in the middle of United's midfield for his first league start since November 19, 2011.
Anders Lindegaard continues ahead of David de Gea in goal for the Red Devils, with Wayne Rooney also returning to Sir Alex Ferguson's XI.
New QPR manager Harry Redknapp is in the stands at Old Trafford to watch his new side and the Premier League's bottom club have made a number of changes.
Kieron Dyer returns to the starting lineup as the likes of Esteban Granero, Samba Diakite and Jose Bosingwa all miss out.
Man Utd: Lindegaard; Rafael, Evans, Ferdinand, Evra; Fletcher, Scholes; Young, Rooney; Welbeck, Van Persie
QPR: Cesar; Mbia, Hill, Nelsen, Traore; Derry, Faurlin; Mackie, Taarabt, Dyer; Cisse