Rotherham United have made five changes to their starting lineup as Neil Redfearn hunts for his first win as manager.
Farrend Rawson has returned after injury but Lee Frecklington and Matt Derbyshire were unable to shake off knocks.
Tomas Kalas starts for Middlesbrough in place of Daniel Ayala, while Grant Leadbitter returns to the starting lineup.
Bruno Zuculini and Diego Fabbrini are dropped to the bench for tonight's match.
Middlesbrough: Konstantopoulos; Nsue, Kalas, Amorebieta, Friend; Adomah, Clayton, Leadbitter, De Pena, Downing; Nugent
Subs: Mejias, Ayala, Gibson, Kike, Stephens, Fabbrini, Zuculini
Rotherham United: Camp; Richardson, Rawson, Collins, Toffolo; Thorpe, Green, G Ward, Andreu; Clarke-Harris, D Ward
Subs: Collin, Broadfoot, Buxton, Smallwood, Maguire, Newell, Bowery