The majority of bookmakers have made Barcelona the clear favourites to advance to the semi-finals of the Champions League at the expense of Paris Saint-Germain over the two legs.
However, the current La Liga leaders may not have it all their own way when they meet for the first time at Parc des Princes on Tuesday night.
PSG have not lost a European game at home for six years. They also have a coach in Carlo Ancelotti who has won the competition both as a player and a manager.
They will also have talisman Zlatan Ibrahimovic available for selection after the Swedish international's two-match suspension was reduced upon appeal.
Meanwhile, visiting Barcelona have injury concerns over left-backs Jordi Alba and Adriano. Should neither be available for selection, youngster Martin Montoya has been tipped to deputise.
The last time that these two met competitively was back in 1997 in the final of the UEFA Cup Winners' Cup. Former Brazil international Ronaldo scored the only goal of the game as Sir Bobby Robson's Barca won 1-0.
Recent form
PSG: WLDWDW
Barcelona: LWWWWD
Possible starting lineups:
PSG: Sirigu; Alex, Maxwell, Thiago Silva, Van der Wiel; Matuidi, Chantome, Pastore, Lucas; Ibrahimovic, Lavezzi
Barcelona: Valdes; Montoya, Mascherano, Pique, Alves; Busquets, Xavi, Iniesta; Fabregas, Pedro; Messi
Sports Mole says: 2-2
No Data Analysis info
