Rayo Vallecano vs. Espanyol (Sunday, 1.00pm)
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Espanyol's battle to escape the La Liga relegation zone will continue on Sunday afternoon when they make the trip to a Rayo Vallecano outfit that are chasing a European finish.
The visitors currently sit 19th in the table, four points from the safety of 17th position, while Rayo are 11th, just two points behind seventh-placed Girona in the race for a Europa Conference League spot.
We say: Rayo Vallecano 2-1 Espanyol
This is a huge match for both sides, and it will be fascinating to see what develops on Sunday. Espanyol desperately need to win, but they have only been victorious three times on their travels this term, while Rayo have been largely strong at home, so we are expecting the hosts to triumph in this contest.
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Atletico vs. Osasuna (Sunday, 3.15pm)
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Atletico Madrid will be bidding to bounce back from their shock result to Elche when they resume their La Liga campaign at home to Osasuna on Sunday afternoon.
Diego Simeone's side are currently third in the table, two points behind second-placed Real Madrid, while Osasuna are ninth, only one point behind seventh-placed Girona.
We say: Atletico Madrid 1-0 Osasuna
Osasuna have often proved to be a tough nut to crack on their travels this season, picking up points in 11 of their 17 away league games. Atletico will be determined to bounce back from their shock loss to Elche, though, and we are backing Simeone's side to secure a narrow victory here.
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Valencia vs. Real Madrid (Sunday, 5.30pm)
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Real Madrid will be bidding to bounce back from their heavy defeat to Manchester City in the Champions League when they resume their La Liga campaign away to Valencia on Sunday night.
Carlo Ancelotti's side are currently second in the table, two points clear of third-placed Atletico Madrid, while Valencia occupy 14th, three points clear of the relegation zone heading into the final straight.
We say: Valencia 1-1 Real Madrid
Real Madrid will be determined to bounce back from their disappointing performance and result against Man City, but Valencia are fighting for their lives towards the bottom and will enter this game in strong form. It would not be a surprise to see an away win here, but we believe that the points will be shared.
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> How Real Madrid could line up against Valencia
> Real Madrid injury, suspension list vs. Valencia
Sevilla vs. Betis (Sunday, 8.00pm)
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Fresh from booking their spot in the Europa League final, Sevilla will resume their La Liga campaign on Sunday evening, welcoming rivals Real Betis for the latest instalment of the Seville derby.
The home side are currently 10th in the table, one point behind seventh-placed Girona, while Real Betis sit comfortably in sixth position, with Manuel Pellegrini's side bidding to qualify for the Europa League.
We say: Sevilla 1-1 Real Betis
This is such a difficult match to call, especially with Sevilla in action on Thursday night. A draw would be a decent result for both teams under the circumstances, and the desire not to lose could make it a cagey affair, with the points potentially being shared in a low-scoring draw.