Eibar vs. Real Valladolid (Thursday, 5.30pm)
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Two sides with nothing but pride to play for in the Spanish top flight will lock horns on Thursday evening as Eibar play host to Real Valladolid in the penultimate gameweek of the season.
Both clubs have amassed 39 points from 36 games this term, with Valladolid currently one spot higher in the table owing to a slightly better goal difference.
We say: Eibar 1-1 Real Valladolid
With both clubs having already guaranteed their safety in La Liga, there is little to nothing riding on this fixture for the two managers. As a result, we are expecting the two sides to play out a draw and remain neck-and-neck in the table heading into the final weekend of the season.
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Athletic Bilbao vs. Leganes (Thursday, 8.00pm)
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Athletic Bilbao and Leganes are in desperate need of victory for different reasons as they face off at San Mames on Thursday in the penultimate round of La Liga fixtures.
Both teams picked up wins at the weekend to keep their league season alive, with Athletic aiming to qualify for Europe and Leganes looking to avoid relegation.
We say: Athletic Bilbao 2-0 Leganes
Leganes have surely left it too late to pull off the great escape. At the very least they require a victory at San Mames on Thursday, but they have lost three of their last four meetings with Athletic and we expect that run to continue here, bringing an end to their spell in the top flight.
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Barcelona vs. Osasuna (Thursday, 8.00pm)
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Barcelona will welcome Osasuna to Camp Nou on Thursday hoping that a victory will be enough to keep their hopes of retaining the La Liga title alive.
The Spanish champions are currently second in the table, four points behind leaders Real Madrid, who will win the title if they manage to beat Villarreal on the same night.
We say: Barcelona 2-0 Osasuna
Osasuna are certainly capable of making it a very uncomfortable evening for Barca, but we are finding it difficult to look past the champions, who have to win and hope that Real Madrid slip up. We cannot see anything other than a routine home victory for Setien's side.
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> How Barcelona could line up against Osasuna
> Barcelona injury, suspension list vs. Osasuna
Real Betis vs. Alaves (Thursday, 8.00pm)
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Alaves head to Real Betis on Thursday evening seeking the victory that they need to guarantee La Liga survival.
The visitors have picked up one point from the last 21 and are four points above the dropzone with two games to go, while Betis are merely jostling for position in mid-table.
We say: Real Betis 1-0 Alaves
Alaves will be looking to put at least another point on the board here, but they have lost their last five away matches without scoring and it is difficult to see that run ending at the Estadio Benito Villamarin, where Betis are unbeaten in nine against Basque opposition.
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Celta Vigo vs. Levante (Thursday, 8.00pm)
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Celta Vigo are still not assured of La Liga safety as they prepare for the visit of mid-table Levante on Thursday evening.
The Celts are winless in five matches and have a four-point buffer on the dropzone with two games to go, while Levante are without a win in four and have slipped to 12th.
We say: Celta Vigo 3-2 Levante
The last three La Liga meetings between Celta and Levante have seen a total of 18 goals - six per game - so this could be an entertaining contest. Celta have far more riding on this game than Levante and we can see them picking up the win needed to make certain of survival.
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Getafe vs. Atletico (Thursday, 8.00pm)
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Getafe welcome local rivals Atletico Madrid to the Coliseum Alfonso Perez on Thursday evening for the penultimate match of their respective La Liga campaigns.
Both capital outfits have been pushing for European qualification throughout the season, but vastly contrasting form since the restart has seen Getafe fall away and Atletico secure their top-four spot already.
We say: Getafe 1-1 Atletico Madrid
These two teams have drawn 17 matches between them this season, and we can see them adding to that tally here. Atletico are in much better form heading into the contest, but Getafe are at home and need the points more than their visitors so we are expecting the two teams to cancel each other out.
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Mallorca vs. Granada (Thursday, 8.00pm)
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Mallorca welcome Granada to the Visit Mallorca Stadium on Thursday evening knowing that only a win will do if they are to keep any hope of La Liga survival alive.
Meanwhile, Granada lie smack bang in the middle of the table and realistically have little to play for as they head into their penultimate game of the season.
We say: Mallorca 1-1 Granada
Even if Mallorca do manage to record their 10th triumph of the season in this game, the result may pale into insignificance depending on the outcome of Alaves' game. Granada have also enjoyed an impressive recent set of results on the road to complement Mallorca's respectable home form, but we cannot separate the two sides for this one.
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Real Madrid vs. Villarreal (Thursday, 8.00pm)
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Real Madrid will welcome Villarreal to the Alfredo Di Stefano Stadium on Thursday night knowing that a win would see them win the 2019-20 La Liga title.
Los Blancos are currently four points clear of second-placed Barcelona in the table with two games left, but it will not be an easy task against a Villarreal side that have been in impressive form since returning to action.
We say: Real Madrid 2-1 Villarreal
Villarreal will be boosted by the return of some key players for this match, and the visitors are certainly capable of securing a positive result. Madrid's form is stunning, though, and we expect Zidane's side to pick up the victory that they need to secure the title with one game to spare.
> Click here to read our full preview for this match
> How Real Madrid could line up against Villarreal
> Real Madrid injury, suspension list vs. Villarreal
Real Sociedad vs. Sevilla (Thursday, 8.00pm)
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Real Sociedad take on Sevilla at Anoeta Stadium on Thursday evening in their penultimate La Liga fixture of the season, aiming to join their opponents in securing European football.
The White and Blues have struggled for form since returning to action last month and are holding onto seventh place, while Sevilla are already assured of a top-four finish.
We say: Real Sociedad 1-1 Sevilla
There is no doubt that Sociedad have dropped off the pace since last month's restart, losing five and drawing two of their last nine matches. Sevilla have won just one of their last eight La Liga games in San Sebastian, however, so we can see this one ending all square.
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Valencia vs. Espanyol (Thursday, 8.00pm)
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Valencia will be aiming to keep their slim hopes of a top-seven finish alive when they welcome already-relegated Espanyol to the Mestalla Stadium in their penultimate game of the season.
Both teams suffered defeats in their most recent outings, with Valencia beaten by a struggling Leganes outfit while Espanyol's losing streak continued against Eibar.
We say: Valencia 2-0 Espanyol
Valencia will be aware that this is a must-win game if they are to stand any chance of qualifying for next season's Europa League. The result may not matter if Sociedad also triumph in midweek, but given Espanyol's abysmal recent record, we are going for a comfortable home victory.