Roma have made three changes to the team that lost to Inter Milan on Saturday for this evening's trip to Sassuolo.
Francesco Totti misses out and is replaced by Seydou Keita, with Miralem Pjanic moving into attacking midfield.
Defenders Mapou Yanga-Mbiwa and Jose Holebas are replaced by Davide Astori and Vasilis Torosidis.
Sassuolo slipped to a 3-2 loss against Hellas Verona on Sunday, and have made four changes for tonight's match.
Dejan Lazarevic, Davide Biondini, Simone Zaza and Domenico Berardi are replaced by Atila Turan, Matteo Brighi, Sergio Floccari and Antonio Floro Flores.
Roma: De Sanctis; Florenzi, Manolas, Astori, Torosidis; Nainggolan, De Rossi, Keita; Pjanic; Ibarbo, Gervinho
Sassuolo: Consigli; Acerbi, Cannavaro, Peluso; Turan, Brighi, Missiroli, Longhi; Sansone, Floccari, Floro Flores
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