Southampton vs. Brentford (Wednesday, 7.30pm)
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Brentford will aim to keep the momentum going from their pulsating seven-goal success over Leeds United when they travel to Southampton for Saturday's Premier League contest at St Mary's.
Thomas Frank's men ran out 5-2 winners over the Whites last time out, while the Saints fell to a 1-0 defeat away to Wolverhampton Wanderers.
We say: Southampton 1-2 Brentford
Southampton have developed into a force to be reckoned with when going behind, but Brentford are just as strong at responding to setbacks, which should lead to an entertaining battle with plenty of goalmouth action.
Frank's side have not been able to replicate their home successes on the road yet, but with Southampton not boasting a penchant for clean sheets, we can envisage the Bees running out narrow winners.
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Brighton vs. Crystal Palace (Wednesday, 7.30pm)
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Just over a month after playing out a 1-1 draw at Selhurst Park, Brighton & Hove Albion and Crystal Palace lock horns at the Amex Stadium for the second M23 derby of the season on Wednesday night.
The two teams are separated by 12 points in the Premier League table, with the Seagulls sitting in seventh place and the Eagles five places further back in 12th.
We say: Brighton & Hove Albion 3-0 Crystal Palace
Crystal Palace have caused Brighton problems on numerous occasions over the years, but their recent form in front of goal is a major concern ahead of their trip to the Amex.
The Seagulls, meanwhile, have been scoring goals for fun so far this campaign, netting at least twice on 13 occasions in the Premier League, and De Zerbi's side will fancy their chances of returning to winning ways with another impressive home triumph on Wednesday.
