Alvaro Morata has been handed the responsibility of leading the Spain attack for their Euro 2016 qualifier against Luxembourg.
The Juventus striker starts as the spearhead of the frontline with support from Pedro, David Silva and Santi Cazorla.
Cesc Fabregas joins Sergio Busquets in the centre of midfield due to the absence of Barcelona's Andres Iniesta, who is unavailable due to injury.
The hosts are also without Sergio Ramos, which allows Marc Barta to start alongside club teammate Gerard Pique at the back.
Burton Albion forward Aurelien Joachim, who has found the net six times at international level, is selected as the lone striker for the visitors.
Spain: Casillas, Juanfran, Pique, Bartra, Alba, Busquets, Fabregas, Cazorla, Silva, Pedro, Morata
Luxembourg: Joubert; Chanot, Delgado, Malget, Jans; Gerson, Martins, Payal, Mutsch; Bensi, Joachim
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