Tottenham Hotspur have a plethora of new absentees to work around for Saturday's Premier League trip to Crystal Palace.

The South American trio of Davinson Sanchez, Giovani Lo Celso and Cristian Romero are reportedly all in hot water with the club after linking up with their national teams for the World Cup qualifiers, with the latter two at the centre of chaos in Argentina's clash with Brazil.

All three players will not be available here due to quarantine - although Sanchez may have been the only one to start anyway - and the Colombian's spot in defence could be filled by Japhet Tanganga as he moves in centrally next to Eric Dier.

Such a move would allow Emerson Royal to make his debut following his deadline day arrival from Barcelona, while Ryan Sessegnon had to withdraw from the England Under-21s squad with a knock but would not have started over Sergio Reguilon.

Oliver Skipp has also enjoyed an extended run in the first team but is also a fresh doubt due to a stiff groin, so Harry Winks could partner the ever-present Pierre-Emile Hojbjerg in the engine room.

Steven Bergwijn (ankle) and Son Heung-min (calf) were two further victims of the international break injury curse, with their possible absences giving Bryan Gil and Lucas Moura chances to impress out wide.

On a lighter note, star man Harry Kane came through the international period unscathed and will aim to build on his tally of 12 goal contributions from 14 games against Palace.

Tottenham possible starting lineup: Lloris; Emerson, Tanganga, Dier, Reguilon; Hojbjerg, Winks; Lucas, Alli, Gil; Kane