Man City vs. Copenhagen (Wednesday, 8.00pm)
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Fresh from their domestic derby triumph at the weekend, Manchester City resume their defence of the Champions League when they welcome Copenhagen to the Etihad Stadium for the second leg of their last-16 tie on Wednesday.
The Citizens boast a two-goal advantage heading into this contest after securing a 3-1 first-leg victory in Denmark three weeks ago.
We say: Manchester City 3-0 Copenhagen (Manchester City to win 6-1 on aggregate)
Complacency should not be an issue for Man City on Wednesday, and even if Guardiola opts to freshen up his side, the Citizens will be regarded as firm favourites to come out on top in the second leg.
Copenhagen can play without fear and will hope to implement some of their impressive spells from the first leg at the Etihad, but the hosts should ultimately have too much for the Danish outfit and we can see the holders securing a safe passage through to the last eight.
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> How Man City could line up against Copenhagen
> Man City injury, suspension list vs. Copenhagen
> Man City vs. Copenhagen: Head-to-head record and past meetings
Real Madrid vs. RB Leipzig (Wednesday, 8.00pm)
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Fuelled by a sense of injustice from the weekend, Real Madrid endeavour to complete the job against RB Leipzig in the second leg of their Champions League last-16 tie at the Bernabeu on Wednesday.
Carlo Ancelotti's men arrive at their headquarters with a 1-0 lead from the first leg three weeks ago, hardly an unassailable advantage for their Bundesliga counterparts to make up.
We say: Real Madrid 3-1 RB Leipzig (Real Madrid win 4-1 on aggregate)
The writing is normally on the wall for Real Madrid's opponents after Los Blancos have won the first leg of a Champions League knockout tie, and Wednesday should be no different given Leipzig's indifferent run of form since the turn of the year.
Rose's men may finally breach Lunin's goal if their finishing resembles that of the weekend's game rather than the first leg, but a fired-up Real Madrid side can hit back even harder to book their place in the quarters and win their eighth CL game on the trot, matching their longest-ever streak in a single campaign.
> Click here to read our full preview for this match
> How Real Madrid could line up against RB Leipzig
> Real Madrid injury, suspension list vs. RB Leipzig
> Real Madrid vs. Leipzig: Head-to-head record and past meetings