Cagliari vs. Frosinone (Sunday, 11.30am)
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Still seeking their first win since promotion, Cagliari aim to get off the mark at the tenth time of asking when they host Frosinone on Sunday.
Both clubs returned to Serie A in the summer, but the Rossoblu's adaptation period has proved tough; meanwhile, their visitors occupy a place in mid-table.
We say: Cagliari 1-2 Frosinone
Cagliari's woes could continue into November, as the Sardinian side are set for a seventh Serie A defeat of the season; they have a sieve-like defence and can be caught out by Frosinone's bright attacking talents more than once.
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Monza vs. Udinese (Sunday, 2.00pm)
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After changing coaches in midweek, Udinese again seek their first league win of the season when they visit mid-table Monza on Sunday.
While the Fruilani languish inside Serie A's drop zone and have just fired Andrea Sottil, their hosts are still unbeaten on home soil.
We say: Monza 1-0 Udinese
Monza are tough to beat - or even score against - at home, while Udinese have proved particularly inept in the final third this season. That is a recipe for the Biancorossi to savour, and they should consign Gabriele Cioffi to defeat on his return to the dugout.
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Inter Milan vs. Roma (Sunday, 5.00pm)
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Having ascended to Serie A's summit after nine rounds of action, Inter Milan aim to keep hold of top spot by beating Roma on Sunday evening.
Inter now host the current club of former boss Jose Mourinho at San Siro, where the visitors' star striker is assured of a 'warm' welcome.
We say: Inter Milan 2-1 Roma
Benefiting from two extra days to recover from their European exertions - and boasting more squad depth than their visitors - Inter are set to make it three wins on the spin in all competitions, cutting Roma's resurgence short. The Giallorossi's absentees are among their most important players, and Inzaghi's men can be ruthless in front of goal.
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Napoli vs. AC Milan (Sunday, 7.45pm)
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The last two champions of Italy clash on Sunday evening, as Scudetto-holders Napoli welcome their predecessors AC Milan to Stadio Maradona.
While the home side have struggled at the start of their title defence, Milan were top of Serie A before losing last weekend, and both have since experienced different fortunes in Europe.
We say: Napoli 1-1 AC Milan
Napoli have failed to beat Milan on home turf for some time now, and that run could be extended this week, as they are still not firing on all cylinders and will be missing their main marksman. Olivier Giroud's goal drought is a concern for the Rossoneri, but he tends to produce in the biggest matches, while Rafael Leao bagged a brace on his last league visit to the Maradona.