Javier Hernandez and Dimitar Berbatov have been selected in attack for the second leg of Manchester United's Europa League last-32 tie against Ajax at Old Trafford.
Wayne Rooney was ruled out of the match on Wednesday with a throat infection.
Phil Jones and Chris Smalling, who were both named in the England squad earlier today, are paired up in the centre of defence.
Elsewhere, Tom Cleverley is joined by Park Ji-Sung in the centre of midfield, with Nani and Ashley Young on the wings.
United hold a 2-0 lead from the first leg in Amsterdam.
Manchester United: De Gea; Rafael, Jones, Smalling, Fabio; Nani, Cleverley, Park, Young; Hernandez, Berbatov
Subs: Amos, Evra, Evans, Carrick, Giggs, Scholes, Welbeck.
Ajax: Vermeer; Alderweireld, Vertonghen, Anita, Sulejmani; Eriksen, De Jong, Lodeiro; Ozbiliz, van Rhijn, Koppers
Subs: Cillessen, Ebecilio, Ooijer, Blind, Serero, Aissati, Klaassen