Real Madrid can temporarily close the gap on second-placed Atletico Madrid to one point on Saturday with a win at Granada in La Liga.
Jose Mourinho's side are unbeaten in the league this year, winning three and drawing one of their four matches.
Luca Alcaraz will take charge of struggling Granada for the first time this weekend after he replaced the sacked Juan Antonio Anquela on Wednesday.
The visitors are still without Iker Casillas and Pepe, while Raphael Varane may keep his place in the side if Sergio Ramos fails to recover in time.
Diego Buonanotte could make his debut for the hosts following a recent move from Malaga.
Recent form
Granada: DWLDWL
Real Madrid: DWWDWD
Possible lineups
Granada: Roberto; Nyom, Diakhate, Mainz, Guilherme; Recio, Santos, Rico, Orellana; Brahimi, Ighalo
Real Madrid: Lopez; Essien, Varane, Carvalho, Arbeloa; Alonso, Khedira; Callejon, Ozil, Ronaldo; Benzema
Sports Mole says: 0-3