The Swiss centre-back signed for the Whites from Arsenal in 2010 and has since gone on to make 68 appearances.
However, the West Londoners have now sanctioned his sale to their La Liga counterparts for an undisclosed fee.
The 28-year-old featured on 15 occasions for the Whites this season.
Restore Data
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Liverpool | 20 | 14 | 5 | 1 | 48 | 20 | 28 | 47 |
| 2 | Arsenal | 21 | 12 | 7 | 2 | 41 | 19 | 22 | 43 |
| 3 | Nottingham ForestNott'm Forest | 21 | 12 | 5 | 4 | 30 | 20 | 10 | 41 |
| 4 | Newcastle UnitedNewcastle | 21 | 11 | 5 | 5 | 37 | 22 | 15 | 38 |
| 5 | Chelsea | 21 | 10 | 7 | 4 | 41 | 26 | 15 | 37 |
| 6 | Manchester CityMan City | 21 | 10 | 5 | 6 | 38 | 29 | 9 | 35 |
| 7 | Aston Villa | 21 | 10 | 5 | 6 | 31 | 32 | -1 | 35 |
| 8 | Bournemouth | 21 | 9 | 7 | 5 | 32 | 25 | 7 | 34 |
| 9 | Fulham | 21 | 7 | 9 | 5 | 32 | 30 | 2 | 30 |
| 10 | Brentford | 21 | 8 | 4 | 9 | 40 | 37 | 3 | 28 |
| 11 | Brighton & Hove AlbionBrighton | 20 | 6 | 10 | 4 | 30 | 29 | 1 | 28 |
| 12 | West Ham UnitedWest Ham | 21 | 7 | 5 | 9 | 27 | 41 | -14 | 26 |
| 13 | Tottenham HotspurSpurs | 21 | 7 | 3 | 11 | 43 | 32 | 11 | 24 |
| 14 | Crystal Palace | 21 | 5 | 9 | 7 | 23 | 28 | -5 | 24 |
| 15 | Manchester UnitedMan Utd | 20 | 6 | 5 | 9 | 23 | 28 | -5 | 23 |
| 16 | Everton | 20 | 3 | 8 | 9 | 15 | 26 | -11 | 17 |
| 17 | Ipswich TownIpswich | 20 | 3 | 7 | 10 | 20 | 35 | -15 | 16 |
| 18 | Wolverhampton WanderersWolves | 21 | 4 | 4 | 13 | 31 | 48 | -17 | 16 |
| 19 | Leicester CityLeicester | 21 | 3 | 5 | 13 | 23 | 46 | -23 | 14 |
| 20 | Southampton | 20 | 1 | 3 | 16 | 12 | 44 | -32 | 6 |
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