Roma vs. Cremonese (Monday, 5.30pm)
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After a winning start last week, Roma return to Stadio Olimpico for their first home game of the season, as Cremonese visit the capital on Monday.
While the Giallorossi saw off Salernitana in their opening fixture, their visitors were unfortunate to be denied a point upon their Serie A return.
We say: Roma 3-1 Cremonese
As early evidence suggests Roma's new front line can be a potent force in Serie A this season, facing Cremonese's defence - which has conceded five times in two competitive matches - will surely suit the hosts.
Roared on by a passionate Giallorossi faithful in their first home fixture, Mourinho's men should expect to win by a two-goal margin.
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Sampdoria vs. Juventus (Monday, 7.45pm)
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Aiming to back up an impressive win in their opening Serie A fixture, Juventus take on Sampdoria at Stadio Luigi Ferraris on Monday.
A 3-0 win over Sassuolo set the Bianconeri on course for a fast start to their league campaign, while Samp suffered defeat at home to Atalanta.
We say: Sampdoria 0-2 Juventus
Even with some of their top talent culled by injury, Juventus should have more than enough guile to pick off a Sampdoria side which has endured abject form for many months now and have failed to benefit from a summer refresh.