Fiorentina vs. Juventus (Saturday, 2.00pm)
© Reuters
Still unbeaten in Serie A, after sealing their second win from four matches, Juventus tackle Fiorentina at Stadio Artemio Franchi on Saturday afternoon.
While the Bianconeri were again indebted to the set-piece prowess of their star striker in Wednesday's 2-0 win over Spezia, his former club fell to their first defeat of the 2022-23 campaign, against Udinese.
We say: Fiorentina 1-2 Juventus
Though not facing the ideal opponent when seeking to end a goal famine, Fiorentina can do so back on home soil - but they may not be able to take any points from what is set to be a close-fought contest.
The hosts rarely lose at home, but Juventus have established a way of grimly grinding out results.
> Click here to read our full preview for this match
AC Milan vs. Inter Milan (Saturday, 5.00pm)
© Reuters
Pitting together the last two champions of Italy, Saturday's Derby della Madonnina sees Scudetto-holders AC Milan tackle an Inter Milan side they deposed as kings of Calcio in May.
The two second city giants convene at San Siro, with the Nerazzurri a point ahead of their oldest rivals in the early Serie A standings.
We say: AC Milan 1-2 Inter Milan
Meeting for the 177th time in Serie A, these two titans have recently risen back to the top of the Italian game through improved management and investment, and there is not a lot to separate them.
However, Inter's ability to find a goal from anywhere across a squad which is slightly deeper than Milan's should prove the difference in the season's first Derby della Madonnina.
> Click here to read our full preview for this match
Lazio vs. Napoli (Saturday, 7.45pm)
© Reuters
Both unbeaten since the start of the Serie A season, Lazio and their southern rivals Napoli clash at Stadio Olimpico on Saturday.
While the hosts were denied a third win from four by conceding a last-gasp equaliser in midweek, their visitors were also held by lower-ranked opponents; leaving the pair locked on eight points apiece in the standings.
We say: Lazio 2-1 Napoli
Though Sarri lost both games against his former employer last season, by an aggregate score of 6-1, he can get the better of Spalletti on this occasion, as Napoli have been more hit-and-miss since a summer of comings and goings in the transfer market; Lazio are the more settled side and should edge a close encounter in the capital.