Daniel Sturridge has not been included in the Liverpool squad for their Europa League tie with Bordeaux after picking up a foot injury in training.
Philippe Coutinho also misses out with a hamstring problem sustained in Saturday's 4-1 win over Manchester City and is replaced by Jordon Ibe.
Kolo Toure is deputising for Martin Skrtel, who is ill, while Joe Allen has slotted into midfield to give a rest to Emre Can.
The fourth and final change made by Jurgen Klopp sees Adam Lallana drop to the bench as Christian Benteke is awarded a start.
Bordeaux have also made four changes, with top goalscorer Wahbi Khazri missing out through suspension.
Liverpool: Mignolet; Clyne, Toure, Lovren, Moreno; Allen, Lucas, Milner; Ibe, Firmino; Benteke
Subs: Bogdan, Lallana, Can, Origi, Skrtel, Brannagan, Randall
Bordeaux: Carrasso; Contento, Sane, Rolan, Saivet; Chantome, Poko, Plasil; Jussie, Yambere, Crivelli
Subs: Ounas, Traore, Diabate, Maurice-Belay, Guilbert, Poundje, Prior
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