Gonzalo Higuain will partner Lorenzo Insigne in the attack for Napoli's Serie A meeting with champions Juventus.
Dries Mertens will start on the bench as the Azzurri go in search of their first win over the Old Lady since March 2014.
Juve goalkeeper Gianluigi Buffon returns to first-team action after being rested in midweek, while Spanish forward Alvaro Morata has recovered from a muscle problem to take up a spot on the bench.
Martin Caceres, Claudio Marchisio, Sami Khedira and Mario Mandzukic are all unavailable to the visitors through injury.
Napoli: Reina; Hysaj, Koulibaly, Ghoulam, Albiol; Loureiro, Jorginho, Hamsik; Callejon, Higuain, Insigne
Subs: Gabriel, Rafael, Strinic, Henrique, Maggio, Chiriches, Chalobah, Valdifiori, Lopez, Kaddouri, Mertens, Gabbiadini
Juventus: Buffon; Chiellini, Bonucci, Padoin, Evra; Zaza, Pogba, Hernanes, Lemina, Pereyra; Dybala
Subs: Neto, Buenacasa, Sandro, Barzagli, Rugani, Cuadrado, Asamoah, Sturaro, Morata
