Andre Villas-Boas has decided to start Frank Lampard, Fernando Torres and Ashley Cole on the bench for tonight's Champions League tie away at Napoli.
There is also no place in the starting lineup for midfielder Michael Essien.
Didier Drogba does start up front, while Gary Cahill will partner David Luiz at the back.
For Napoli, defender Hugo Campagnaro has been passed fit to start despite a muscular problem.
Napoli: De Sanctis; Aronica, Campagnaro, Cannavaro; Maggio, Inler, Zuniga, Gargano, Hamsik; Cavani, Lavezzi
Chelsea: Cech; Ivanovic, David Luiz, Cahill, Bosingwa; Ramires, Meireles, Malouda; Sturridge, Drogba, Mata