Lecce vs. Frosinone (Saturday, 2.00pm)
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Lecce and Frosinone are separated by a place in the Serie A table heading into Saturday's gameweek 16 meeting at Stadio Via del Mare.
The home side have not won a game in Italy's top division in three months, but they could leapfrog the visiting team by ending that unwanted wait without winning.
We say: Lecce 2-1 Frosinone
Even though another Lecce tie should not surprise observers, we are backing D'Aversa's troops to end their extended wait for maximum points against Frosinone this weekend.
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Napoli vs. Cagliari (Saturday, 5.00pm)
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After securing a place in the Champions League's last 16, Napoli aim to get back on track in Serie A when they continue their faltering title defence against Cagliari on Saturday.
The Scudetto holders beat Braga in midweek, but last week's loss to Juventus left them 14 points off the top of the table; meanwhile, Cagliari's climb away from the drop zone continues.
We say: Napoli 2-0 Cagliari
Napoli are still some way short of last season's scintillating form, but they should have enough gas left in the tank to secure back-to-back wins by beating Cagliari. The Isolani have picked up just two points on the road this term, so even their hosts' dire home record may not help them.
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Torino vs. Empoli (Saturday, 7.45pm)
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Seeking a top-half spot in the Serie A standings, mid-table Torino host lowly Empoli on Saturday evening.
While a win would take Toro into the top 10, their visitors need points to pull themselves out of the relegation zone.
We say: Torino 1-0 Empoli
A goal-fest should not be expected in Saturday's late kickoff, as both teams are far from prolific and average less than one goal per game. Instead, a single strike may decide matters, with the hosts most likely to produce it.