Fulham vs. Brighton (Tuesday, 7.30pm)
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Fulham can stretch their unbeaten run at Craven Cottage to three consecutive Premier League encounters on Tuesday when they host Brighton & Hove Albion for the first time since the 2020-21 campaign.
Last season's Championship winners dropped their first encounter of the new top-flight campaign last Saturday, 2-1 versus Arsenal, while Albion are one of only five EPL sides without a defeat this season, beating Leeds United 1-0 over the weekend.
We say: Fulham 0-1 Brighton & Hove Albion
Brighton look incredibly determined and composed in the early portion of the season, while collectively, they have rarely suffered a lapse in concentration.
The Seagulls' overall commitment should carry them to another victory against a Fulham side, who have played well but have also had their share of breakdowns on the back end.
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Crystal Palace vs. Brentford (Tuesday, 7.30pm)
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Fresh off a hard-fought defeat to the reigning two-time Premier League Champions on Saturday, Crystal Palace return to Selhurst Park in search of their first London Derby victory of the domestic season when they host Brentford on Tuesday.
The Eagles let a two-goal lead against Man City slip away in their previous fixture, losing 4-2, while Brentford came back to earn a point once again, drawing Everton 1-1.
We say: Crystal Palace 2-2 Brentford
There is a lot to be encouraged about in the early going for both of these teams, who have shown plenty of attacking intent so far this season, and we believe the resiliency of Brentford will come to the forefront once again to steal a couple of points from the home side.
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Southampton vs. Chelsea (Tuesday, 7.45pm)
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Chelsea head into their Premier League fixture with Southampton on Tuesday evening looking to make further progress up the standings.
At a time when Chelsea sit in sixth position on the back of the weekend's win over Leicester City, 14th-placed Southampton can move ahead of their next opponents with success at St Mary's.
We say: Southampton 1-1 Chelsea
Although Chelsea came through with three points at the weekend, they had to work with 10 men for over an hour. Also taking their less recovery time into consideration, we are backing Southampton to earn a share of the spoils, potentially even maximum points if they are more ruthless in the final third.
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> How Chelsea could line up against Southampton
> Chelsea injury, suspension list vs. Southampton
Leeds vs. Everton (Tuesday, 8.00pm)
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Leeds United head into Tuesday's fixture with Everton looking to strengthen their hold of a place in the top six of the Premier League standings.
While the Toffees make the trip to Elland Road unbeaten in their last two outings, they are yet to record a league win during 2022-23.
We say: Leeds United 2-0 Everton
Now that they have another frontline striker in their ranks, Everton will be more optimistic about performing in the final third. Nevertheless, we cannot back against Leeds in this fixture, who already have three successive wins at Elland Road this season.