Manchester United have been drawn against Saint-Etienne in the last 32 of the Europa League.
Jose Mourinho's side managed to avoid Roma, Ajax, Schalke 04, Lyon and Besiktas in the first knockout round of the tournament.
The Red Devils will face a team who currently sit eighth in Ligue 1 and have won fewer than half of their 17 domestic fixtures.
United midfielder Paul Pogba may come up against his brother Florentin, who has been playing for the club since his 2012 switch from Sedan.
The two clubs have faced one another just twice before, which was in 1977, with one of the fixtures ending in a draw and the other being won by United.
Meanwhile, Tottenham Hotspur, who dropped into the second-tier European tournament as a result of finishing third in their Champions League group, will face Gent in the last-32 stage.
The first legs will be played on February 16, with the return legs one week later.
Europa League last-32 ties in full:
Athletic Bilbao vs. Apoel FC
Legia Warszaw vs. Ajax
Anderlecht vs. Zenit
FC Astra Giurgiu vs. Genk
Manchester United vs. Saint-Etienne
Villarreal vs. Roma
Ludogorets vs. Copenhagen
Celta Vigo vs. Shakhtar Donetsk
Olympiacos vs. Osmanlispor
Gent vs. Tottenham
FC Rostov vs. Sparta Prague
Krasnodar vs. Fenerbahce
Borussia Monchengladbach vs. Fiorentina
AZ Alkmaar vs. Lyon
Hapoel Be'er Sheva vs. Besiktas
PAOK FC vs. Schalke
