Christian Benteke has been handed his first start under manager Jurgen Klopp as the German coach selects a strong side to face Rubin Kazan in the Europa League.
The Reds are yet to win a game in the competition this season following three draws, and tonight they have installed attacking presence in Jordon Ibe, and Roberto Firmino.
Philippe Coutinho and Adam Lallana drop to the bench, while Joe Allen has replaced Lucas Leiva and Dejan Lovren has come in for centre-back Martin Skrtel.
Nathaniel Clyne, Alberto Moreno, Mamadou Sakho, Emre Can and James Milner have all kept their places in the team for tonight's Group B fixture.
Meanwhile, the home side have the attacking threat of Marko Devic, but they will be without Oleg Kuzmin, who is serving a suspension after getting sent off in the fixture at Anfield.
Rubin Kazan: Ryzhikov; Kverkvelia, Cotugno, Kambolov, Nabiullin; Carlos Eduardo, Kislyak, Gokdeniz Karadeniz, Georgiev; Devic, Kanunnikov
Subs: Haghighi, Lemos, Ustinov, Akhmetov, Bilyaletdinov, Ozdoev, Dyadyun
Liverpool: Mignolet; Clyne, Sakho, Lovren, Moreno; Can, Allen, Milner; Ibe, Firmino; Benteke
Subs: Bogdan, Coutinho, Lallana, Lucas, Origi, Brannagan, Skrtel
Follow Sports Mole's live text commentary of the game here.
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